By TRKnight2007 December 2, 2009 1,172 4

Prozac (Fluoxetine) is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Prozac is approved for the treatment of major depression (including pediatric depression), obsessive-compulsive disorder (in both adult and pediatric populations), bulimia nervosa, anorexia nervosa, panic disorder and premenstrual dysphoric disorder. Despite the availability of newer agents, it remains extremely popular. Over 22.2 million prescriptions for generic formulations of fluoxetine were filled in the United States in 2007, making it the third most prescribed antidepressant.

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Reviews (4 reviews)

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[email protected] May 8, 2015 at 6:20 am   
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This med worked for me very well for about 5 yrs ending on highest dosage given and out of the blue it just quit working. Had to find new med which can be bad because sometimes have to stop med for short time before beginning another. Time is important when a person has severe chronic depression. There are a few new meds now that work in a different way in the brain. I take pristique and it's working great .

saber32 October 13, 2011 at 2:57 am   
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i had a reaction to this medication i got taking off of this med

Dolphin1020 May 30, 2011 at 8:20 pm   
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I really didn't like this medicine. It had the exact opposite effects for me - it really made my depression much worse. I'm probably a special case though, so don't just use my opinion when looking for an anti-depressant. It has been around a very long time and is very well known, so is probably pretty reliable. It's also one of the few that's been FDA approved for teens (I think).

TRKnight2007 December 2, 2009 at 11:11 am   
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It has been around a long time, so it has been through many clinical trials as well as a large number of prescriptions. By now, the risk factors are well known.


Common adverse effects include nausea (22% vs 9% for placebo), insomnia (19% vs 10% for placebo), somnolence (12% vs 5% for placebo), anorexia (10% vs 3% for placebo), anxiety (12% vs 6% for placebo), nervousness (13% vs 8% for placebo), asthenia (11% vs 6% for placebo) and tremor (9% vs 2% for placebo). Those that most often resulted in interruption of the treatment were anxiety, insomnia, and nervousness (1-2% each), and in pediatric trials—mania (2%). Similarly to other SSRIs, sexual side effects are common with fluoxetine; they include anorgasmia and reduced libido.